Research and Training

IHOPE will have three primary focus areas: Big Data analysis, Health Economics and Clinical and Public Health Research. The large clinical data available with LVPEI for the last 30 years, including data from remote rural areas through LVPEI’s primary health centres will drive the research at IHOPE.

The LVPEI Network famously known as the LVPEI pyramid​​

The in-house EyeSmartTM Electronic Medical Record system, implemented across the LVPEI network enabling the digitization of 5 million patient consults,  will be leveraged for big data analysis forming the backbone of IHOPE. While the big data analysis of health data can help us answer important clinical and public health research questions in eye health, data mining for economic related information in EyeSmart will allow us to address relevant questions in health economics like cost-effectiveness of interventions and patient reported outcomes.

Aims and Objectives

Research Centre

Generate new knowledge and disseminate the best practices in clinical research, health economics and public health in vision sciences through big data.

Clinician Scientists

Create a pool of trained clinician scientists with expertise at the intersection of the above domains.

Training Centre

Develop a training centre for clinicians to assess and perform research, evaluate cost-effectiveness, and analyze big data.

Research at IHOPE will focus on these primary areas to begin with:

Through focus on research and training, the center strives to achieve the following outcomes in its first 5 years of operations:

Training and Capacity Building

In addition to research, training clinician scientists is an important focus of IHOPE. This will be done in two ways:

a) Clinical Research Training Programme (CRTP):
The Clinical Research Training Programme is embedded as part of the Clinical/Public Health Research Centre (CRC) Grant by DBT Wellcome Trust India Alliance to set up IHOPE. As per India Alliance, “The purpose of the CRTP programme is to fund mentored research training Fellowships to medical graduates and post-graduates to integrate basic and clinical/public health research, provide training opportunities in diverse areas of research relevant to India’s health priorities and provide knowledge and skills to prepare trainees for careers in health research.”

Three CRTP Fellowships have been awarded to IHOPE, as part of the CRC grant.

The proposed CRTP while focusing on research will further add to the existing education and training programs at LVPEI. The chosen CRTP Fellows would be clinicians trained in all areas of research, would design, implement, analyze and publish work in accordance with the CRC curriculum that will be put in place.

B) Capacity Building through IHOPE​​

In addition to the Clinical Research Training Programme Fellowships, we also plan to roll out certain online courses to train a larger pool of clinicians in areas relevant to IHOPE. We aim to build on LVPEI as well as IIPH and IIMA’s expertise and experience in running training courses and aim to translate our strength into a professional education program in this field.

We plan to start the following modules for external and internal candidates in the next 3 years:
(a) IGH GCP guidelines
(b) Biostatistics
(c) Randomized controlled trials
(d) Epidemiology and Public Health
(e) Health outcomes research
(f) Cost-effectiveness of interventions

We expect to roll out these courses in a phased manner over the next 3 years, and hope to train over 50 clinicians (internal and external) per year after 5 years.

BIG DATA
Year 1

a) Data Exploration and Preparation: digital systems and platforms
b) Data Representation and Transformation: Data pre-processing and big data query writing using Spark and SQL platforms

Year 2

c) Computing with Data: Data algorithms and machine learning models

Year 3

d) Data Modeling from input and automated analysis

Year 4

e) Data Visualization and Presentation: interactive analytics, business intelligence and KPI development
f) Science about Data Science: Newer data science techniques and their relevance to the existing projects

Our Mentors

Dr Anthony Vipin Das, LVPEI
Dr Mehul Mehta, Harvard University

HEALTH ECONOMICS
Year 2

a) Introduction to Economics
b) Cost-benefit and Cost-utility analysis

Year 3

c) Demand and Supply of Health Insurance
d) Health Insurance markets
e) Pharmaceutical Industry and Drug Pricing

Year 4

f) Competition, Markets and Public Policy for Healthcare
g) Ethics and Economics in Healthcare and Pharmaceutical Markets
h) Global Health Systems and India
i) Technology and Healthcare in India and the World

Our Mentors

Dr Raja Narayanan, LVPEI
Prof Chirantan Chatterjee, IIMA

PUBLIC HEALTH
Year 1

a) Measuring health and disease
b) Types of studies
c) Basic Biostatistics

Year 2

d) Causation in epidemiology
e) Diagnostic Test Interpretation
f) Interpretation of results of a study

Year 3

g) Evidence-based medicine
h) Advanced statistics using R software

Year 4

i) Field project

Our Mentors

Dr Rohit Khanna, LVPEI
Dr GVS Murthy, IIPH
Dr Mehul Mehta, Harvard University
Ms Ashalatha, LVPEI
Dr G Chandra Sekhar, LVPEI

CLINICAL RESEARCH
Our Mentors

Dr Raja Narayanan, LVPEI
Dr Siddharth Dikshit, LVPEI
Dr Sayan Basu, LVPEI
Dr G Chandra Sekhar, LVPEI